Peptide-Based Agents for Cancer Treatment: Current Applications and Future Directions

نویسندگان

چکیده

Peptide-based strategies have received an enormous amount of attention because their specificity and applicability. Their tumor-targeting ability are applied to diagnosis treatment for cancer patients. In this review, we will summarize recent advancements future perspectives on peptide-based treatment. The literature search was conducted identify relevant articles It performed using PubMed in English until June 2023. Information clinical trials also obtained from ClinicalTrial.gov. Given that several advantages such as targeted delivery the diseased area, personalized designs, relatively small sizes, simple production process, bioactive peptides having anti-cancer activities (anti-cancer or ACPs) been tested pre-clinical settings trials. capability tumor targeting is essentially useful peptide–drug conjugates (PDCs), diagnosis, image-guided surgery. Immunomodulation with peptide vaccines has extensively Despite advantages, FDA-approved agents solid still limited. This review provide a detailed overview current approaches, design strategies, routes administration, new technological advancements. We highlight success limitations therapies

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2023

ISSN: ['1661-6596', '1422-0067']

DOI: https://doi.org/10.3390/ijms241612931